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	Provedor de dados BJMBR (1) Autor Buffolo,E. (1) Carvalho,M.H.C. (1) Chagas,A.C.P. (1) Dantas,A.P. (1) Ferreiro,C.R. (1) Luz,P.L. da (1) Scavone,C. (1) Souza,L.C.B. (1) Mais... Palavra-chave Heart failure (1) Left ventricle ejection fraction (1) Nitric oxide synthase (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2004 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Expression of inducible nitric oxide synthase is increased in patients with heart failure due to ischemic disease BJMBR Ferreiro,C.R.; Chagas,A.C.P.; Carvalho,M.H.C.; Dantas,A.P.; Scavone,C.; Souza,L.C.B.; Buffolo,E.; Luz,P.L. da. The objective of the present study was to determine the relationship between nitric oxide synthases (NOS) and heart failure in cardiac tissue from patients with and without cardiac decompensation. Right atrial tissue was excised from patients with coronary artery disease (CAD) and left ventricular ejection fraction (LVEF) <35% (N = 10), and from patients with CAD and LVEF >60% (N = 10) during cardiac surgery. NOS activity was measured by the conversion of L-[H³]-arginine to L-[H³]-citrulline. Gene expression was quantified by the competitive reverse transcription-polymerase chain reaction. Both endothelial NOS (eNOS) activity and expression were significantly reduced in failing hearts compared to non-failing hearts: 0.36 ± 0.18 vs 1.51 ± 0.31 pmol... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nitric oxide synthase; Left ventricle ejection fraction; Heart failure. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000900005 Registros recuperados: 1 Primeira ... 1 ... Última

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